Friday 11 March 2011

Ototoxicity Article

Good Article on Ototoxicity here:


http://emedicine.medscape.com/article/857679-overview


.......Of all ototoxic drugs, the aminoglycosides are the most vestibulotoxic, although they vary greatly in their differential effects on the vestibular and cochlear systems.2 Kanamycin, amikacin, neomycin, and dihydrostreptomycin are preferentially cochleotoxic. Gentamicin affects both cochlear and vestibular systems......


And a Tinnitus based one here:


http://www.tinnitusformula.com/infocenter/articles/conditions/ototox.aspx

Personally I wasn't aware of the effects of so many diuretics which seem in common usage. The Aminoglycocides, NSAIDs and general toxicity of the metals used in Chemotherapy were well covered on our dispensing course, but not the others.

The slightly disturbing/ironic issue with some of the known Tinnitus causes is that they seem also to be used as Tinnitus inhibitors........

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